Fredlake, C.P. and Hert, D.G. and Kan, C.W. and et al, . (2008) Ultrafast DNA sequencing on a microchip by a hybrid separation mechanism that gives 600 bases in 6.5 minutes. PNAS, 105 (2). pp. 476-481.
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Abstract
To realize the immense potential of large-scale genomic sequencing after the completion of the second human genome (Venter’s), the costs for the complete sequencing of additional genomes must be dramatically reduced. Among the technologies being developed to reduce sequencing costs, microchip electrophoresis is the only new technology ready to produce the long reads most suitable for the de novo sequencing and assembly of large and complex genomes.
| Item Type: | Article |
|---|---|
| Additional Information: | We thank Dr. Karl Putz for help with rheology measurements. This publication was made possible by National Institutes of Health Grants 2 R01 HG001970-07, from the National Human Genome Research Institute, and 5 U01 AI0161297-07, from the National Institute of Allergy and Infectious Diseases. Additional support was provided by the National Science Foundation through Northwestern University Nanoscale Science and Engineering Center Grant EEC-0647560 and by the Department of Homeland Security (DHS) under the DHS Scholarship and Fellowship Program. |
| Uncontrolled Keywords: | Ultrafast DNA sequencing, Hybrid separation mechanism |
| Author Affiliation: | Northwestern University, Evanston |
| Subjects: | Crop Improvement |
| Divisions: | Other Crops |
| Depositing User: | Mr Arbind Seth |
| Date Deposited: | 01 Jan 2013 09:21 |
| Last Modified: | 01 Jan 2013 09:21 |
| Official URL: | http://www.pnas.org/content/105/2/476.full.pdf+htm... |
| URI: | http://eprints.icrisat.ac.in/id/eprint/9143 |
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