Krattinger, S.G. and Jordan, D.R. and Mace, E.S. and et al, . (2013) Recent emergence of the wheat Lr34 multi-pathogen resistance: insights from haplotype analysis in wheat, rice, sorghum and Aegilops tauschii. Theoretical and Applied Genetics , 126 (4). pp. 663-672.
![[img]](http://eprints.icrisat.ac.in/style/images/fileicons/application_pdf.png) |
PDF
- Published Version
Restricted to ICRISAT researchers only |
Abstract
Spontaneous sequence changes and the selection of beneficial mutations are driving forces of gene diversification and key factors of evolution. In highly dynamic co-evolutionary processes such as plant-pathogen interactions, the plant’s ability to rapidly adapt to newly emerging pathogens is paramount. The hexaploid wheat gene Lr34, which encodes an ATP-binding cassette (ABC) transporter, confers durable field resistance against four fungal diseases. Despite its extensive use in breeding and agriculture, no increase in virulence towards Lr34 has been described over the last century. The wheat genepool contains two predominant Lr34 alleles of which only one confers disease resistance. The two alleles, located on chromosome 7DS, differ by only two exon-polymorphisms. Putatively functional homoeologs and orthologs of Lr34 are found on the B-genome of wheat and in rice and sorghum, but not in maize, barley and Brachypodium. In this study we present a detailed haplotype analysis of homoeologous and orthologous Lr34 genes in genetically and geographically diverse selections of wheat, rice and sorghum accessions. We found that the resistant Lr34 haplotype is unique to the wheat D-genome and is not found in the B-genome of wheat or in rice and sorghum. Furthermore, we only found the susceptible Lr34 allele in a set of 252 Ae. tauschii genotypes, the progenitor of the wheat D-genome. These data provide compelling evidence that the Lr34 multi-pathogen resistance is the result of recent gene diversification occurring after the formation of hexaploid wheat about 8,000 years ago.
| Item Type: | Article |
|---|---|
| Author Affiliation: | CSIRO, Canbera, Australia, University of Zurich, Zollikerstr. 107, 8008, Zurich, The University of Queensland, Warwick, QLD, 4370, Australia Agri-Science Queensland, 604 Yangan Road, Warwick, QLD, 4370, Australia , IRRI, Metro Manila, Philippines, University of California, Davis, CA, 95616, USA |
| Subjects: | Plant Protection Statistics and Experimentation Crop Improvement |
| Divisions: | Sorghum |
| Depositing User: | Mr. SanatKumar Behera |
| Date Deposited: | 06 Nov 2012 04:46 |
| Last Modified: | 22 May 2013 04:57 |
| Official URL: | http://dx.doi.org/10.1007/s00122-012-2009-1 |
| URI: | http://eprints.icrisat.ac.in/id/eprint/8674 |
Actions (login required)
 |
View Item |
