Cyclopiazonic Acid Residues in Milk and Eggs

Dorner, J.W. and Cole, R.J. and Erlington, D.J. and Suksupath, S. and McDowell, G.H. and Bryden, W.L. (1994) Cyclopiazonic Acid Residues in Milk and Eggs. Journal of Agricultural and Food Chemistry, 42 (7). pp. 1516-1518.

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Abstract

The mycotoxin cyc1opiazonic acid (CPA) was detected in the milk from ewes and the eggs from chickens that were given oral doses of the toxin. Three lactating ewes were given CPA for 2 days at a rate of 5 mg/kg of live weight. Thin-layer chromatographic analyses of dried, defatted milk samples showed that CPA was present in milk at an average concentration of 236 ng/g within 24 h of the illstdose. The concentration of CPA reached a higb of 568 ng/g, but none was detectable by the ninth day after the first dose. Laying hens were given oral doses of CPA in two separate studies: an acute study over 9 days with dose groups of 0.0, 2.5, 5.0, and 10.0 mg/kg of live weight and a chronic study over 4 weeks with dose groups of 0.0, 1.25, and 2.5 mg/kg of live weight. Eggs from birds in all dose groups throughout both studies contained CPA. The concentrations of CPA were much higher in egg whites than in egg yolks, averaging approximately 100 and 10 ng/g, respectively.

Item Type: Article
Uncontrolled Keywords: Mycotoxins, Aspergillus {lavus, Penicillium, sheep, chickens
Author Affiliation: National Peanut Research Laboratory, Agricultural Research Service, U.S. Department of Agriculture, 1011 Forrester Drive S.E., Dawson, Georgia 31742, and Department of Animal Science, University of Sydney, Camden, New South Wales 2570, Australia
Subjects: Plant Protection
Soil Science and Microbiology > Microbiology
Plant Physiology and Biochemistry > Biochemistry
Divisions: General
Depositing User: Mr. SanatKumar Behera
Date Deposited: 08 Aug 2012 05:04
Last Modified: 08 Aug 2012 05:05
Official URL: http://dx.doi.org/10.1021/jf00043a023
URI: http://eprints.icrisat.ac.in/id/eprint/7236

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