Lin, Z. and Li, X. and Shannon, L. M. and et al, . (2012) Parallel domestication of the Shattering1 genes in cereals. Nature genetics. 6 pp..
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Abstract
A key step during crop domestication is the loss of seed shattering. Here, we show that seed shattering in sorghum is controlled by a single gene, Shattering1 (Sh1), which encodes a YABBY transcription factor. Domesticated sorghums harbor three different mutations at the Sh1 locus. Variants at regulatory sites in the promoter and intronic regions lead to a low level of expression, a 2.2-kb deletion causes a truncated transcript that lacks exons 2 and 3, and a GT-to-GG splice-site variant in the intron 4 results in removal of the exon 4. The distributions of these non-shattering haplotypes among sorghum landraces suggest three independent origins. The function of the rice ortholog (OsSh1) was subsequently validated with a shattering-resistant mutant, and two maize orthologs (ZmSh1-1 and ZmSh1-5.1+ZmSh1-5.2) were verified with a large mapping population. Our results indicate that Sh1 genes for seed shattering were under parallel selection during sorghum, rice and maize domestication.
| Item Type: | Article |
|---|---|
| Author Affiliation: | Department of Agronomy, Kansas State University, Manhattan, Kansas, USA. |
| Subjects: | Crop Improvement |
| Divisions: | Millet Sorghum |
| Depositing User: | Mr Siva Shankar |
| Date Deposited: | 21 May 2012 10:59 |
| Last Modified: | 21 May 2012 11:00 |
| Official URL: | http://dx.doi.org/10.1038/ng.2281 |
| URI: | http://eprints.icrisat.ac.in/id/eprint/5583 |
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