Lam, H. and et al, . (2010) Resequencing of 31 wild and cultivated soybean genomes identifies patterns of genetic diversity and selection. Nature Genetics, 42 (12). pp. 1053-1059.
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Abstract
We report a large-scale analysis of the patterns of genome-wide genetic variation in soybeans. We re-sequenced a total of 17 wild and 14 cultivated soybean genomes to an average of approximately ×5 depth and >90% coverage using the Illumina Genome Analyzer II platform. We compared the patterns of genetic variation between wild and cultivated soybeans and identified higher allelic diversity in wild soybeans. We identified a high level of linkage disequilibrium in the soybean genome, suggesting that marker-assisted breeding of soybean will be less challenging than map-based cloning. We report linkage disequilibrium block location and distribution, and we identified a set of 205,614 tag SNPs that may be useful for QTL mapping and association studies. The data here provide a valuable resource for the analysis of wild soybeans and to facilitate future breeding and quantitative trait analysis.
| Item Type: | Article |
|---|---|
| Author Affiliation: | The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.BGI-Shenzhen, Shenzhen, China. Key Laboratory of Genomics, Ministry of Agriculture, BGI-Shenzhen, China Institute of Crop Sciences, The Chinese Academy of Agricultural Sciences, Beijing, China Department of Biology, University of Copenhagen, Copenhagen, Denmark |
| Subjects: | Crop Improvement |
| Divisions: | Common Bean |
| Depositing User: | Mr. SanatKumar Behera |
| Date Deposited: | 09 Mar 2012 11:56 |
| Last Modified: | 09 Mar 2012 11:57 |
| Official URL: | http://dx.doi.org/10.1038/ng.715 |
| URI: | http://eprints.icrisat.ac.in/id/eprint/3721 |
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