Wang, Z. and Gerstein, M. and Michael, S. (2009) RNA-Seq: a revolutionary tool for transcriptomics. Nature Reviews Genetics, 10 (1). pp. 57-63.
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Abstract
RNA-Seq is a recently developed approach to transcriptome profiling that uses deep-sequencing technologies. Studies using this method have already altered our view of the extent and complexity of eukaryotic transcriptomes. RNA-Seq also provides a far more precise measurement of levels of transcripts and their isoforms than other methods. This article describes the RNA-Seq approach, the challenges associated with its application, and the advances made so far in characterizing several eukaryote transcriptomes
| Item Type: | Article |
|---|---|
| Author Affiliation: | Department of Molecular, Cellular and Developmental Biology, Yale University, 219 |
| Subjects: | Plant Production > Production Practices |
| Divisions: | General |
| Depositing User: | Syamala |
| Date Deposited: | 11 May 2011 05:03 |
| Last Modified: | 11 May 2011 05:03 |
| Official URL: | http://dx.doi.org/10.1038/nrg2484 |
| URI: | http://eprints.icrisat.ac.in/id/eprint/2008 |
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