Garcia-Canas, V. and Simo, C. and Leon, C. and Cifuentes, A. (2010) Advances in nutrigenomics research: novel and future analytical approaches to investigate the biological activity of natural compounds and food functions. Journal of Pharmaceutical and Biomedical Analysis, 51 (2). pp. 290-304.
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Abstract
In recent years, nutrition research has moved from classical epidemiology and physiology to molecular biology and genetics. Following this trend, Nutrigenomics has emerged as a novel and multidisciplinary research field in nutritional science that aims to elucidate how diet can influence human health. It is already well known that bioactive food compounds can interact with genes affecting transcription factors, protein expression and metabolite production. The study of these complex interactions requires the development of advanced analytical approaches combined with bioinformatics. Thus, to carry out these studies Transcriptomics, Proteomics and Metabolomics approaches are employed together with an adequate integration of the information that they provide. In this article, an overview of the current methodologies and a thorough revision of the advances in analytical technologies and their possibilities for future developments and applications in the field of Nutrigenomics is provided.
| Item Type: | Article |
|---|---|
| Author Affiliation: | Institute of Industrial Fermentations (CSIC), Juan de la Cierva 3, Madrid, Spain |
| Subjects: | Crop Improvement > Genetics/Genomics |
| Divisions: | Other Crops |
| Depositing User: | Sandhya Gir |
| Date Deposited: | 14 Feb 2011 17:08 |
| Last Modified: | 14 Feb 2011 17:09 |
| Official URL: | http://dx.doi.org/10.1016/j.jpba.2009.04.019 |
| URI: | http://eprints.icrisat.ac.in/id/eprint/1507 |
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