Molecular biology of the Bunyaviridae

Elliott, R.M. (1990) Molecular biology of the Bunyaviridae. Journal of General Virology, 71 (3). pp. 501-522.

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Abstract

More than 300 viruses, mostly arthropod-transmitted, are classified into the family Bunyaviridae, making it one of the largest groupings of animal viruses (Karabatsos, 1985). Until relatively recently these viruses were somewhat the ‘Cinderellas’ of animal virology, but with the increased recognition of their role in human diseases together with the results generated by the application of molecular techniques, the Bunyaviridae have achieved greater respectability. Rift Valley fever, Crimean-Congo haemorrhagic fever and California encephalitis viruses are serious human pathogens that are classified in the family Bunyaviridae. In the tropics febrile illnesses are often diagnosed under the ‘great umbrella’ (Downs, 1975) of malaria and treated as such; in fact many cases are probably caused by members of the Bunyaviridae, although true diagnosis is rarely achieved (Shope, 1985). Hantaan and related viruses, the causative agents of haemorrhagic fever with renal syndrome, are now recognized as belonging to the Bunyaviridae (Schmaljohn & Dalrymple, 1983) and cause a severe haemorrhagic disease with significant mortality throughout Asia, especially in China

Item Type:	Article
Uncontrolled Keywords:	Viruses, Bunyaviridae, Hantaan, Arboviruses, RNA segments, M RNA segment
Author Affiliation:	Institute of Virology, University of Glasgow, Church Street, Glasgow G11 5JR, U.K.
Subjects:	Soil Science and Microbiology > Microbiology Crop Improvement > Biotechnology
Divisions:	General
Depositing User:	Ms Ishrath Durafsha
Date Deposited:	19 May 2014 09:12
Last Modified:	19 May 2014 09:12
Official URL:	http://dx.doi.org/10.1099/0022-1317-71-3-501
URI:	http://eprints.icrisat.ac.in/id/eprint/13003

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