Wu, Y. and Yuan, L. and Messing, J. and et al, . (2013) Mutation in the seed storage protein kafirin creates a high-value food trait in sorghum. Nature Communications (4-2217). pp. 1-7.
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Abstract
Sustainable food production for the earth’s fast-growing population is a major challenge for breeding new high-yielding crops, but enhancing the nutritional quality of staple crops can potentially offset limitations associated with yield increases. Sorghum has immense value as a staple food item for humans in Africa, but it is poorly digested. Although a mutant exhibiting high-protein digestibility and lysine content has market potential, the molecular nature of the mutation is previously unknown. Here, building on knowledge from maize mutants, we take a direct approach and find that the high-digestible sorghum phenotype is tightly linked to a single-point mutation, rendering the signal peptide of a seed storage protein kafirin resistant to processing, indirectly reducing lysine-poor kafirins and thereby increasing lysine-rich proteins in the seeds. These findings indicate that a molecular marker can be used to accelerate introduction of this high nutrition and digestibility trait into different sorghum varieties.
| Item Type: | Article |
|---|---|
| Additional Information: | Referenced accessions GenBank/EMBL/DDBJ KF141792 |
| Author Affiliation: | Waksman Institute of Microbiology, Rutgers University, 190 Frelinghuysen Road, Piscataway, New Jersey 08854, USA |
| Subjects: | Crop Improvement |
| Divisions: | Sorghum |
| Depositing User: | Mr Siva Shankar |
| Date Deposited: | 24 Aug 2013 00:21 |
| Last Modified: | 27 Aug 2013 08:17 |
| Official URL: | http://dx.doi.org/10.1038/ncomms3217 |
| URI: | http://eprints.icrisat.ac.in/id/eprint/11538 |
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