Lu, T. and Vargas, D. and Franzblau, S.G. and Fischer, N.H. (1995) Diterpenes from Solidago rugosa. Phytochemistry, 32 (2). pp. 451-456.
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Abstract
Investigation of the roots and aerial parts of Solidago rugosa afforded the known diterpenes kolavenol, hardwickiic acid, (−)-kaur-16-en-19-oic acid, (+)-manool, (+)-3β-hydroxymanool, manoyl oxide and ent-abietic acid. In addition, the new labdane diterpene (+)-18-tigloyloxymanool and four new ent-abietanes were obtained. The structures of all known and new compounds were elucidated by spectroscopic methods, especially high-field 1H and 13C NMR, and inverse 1H-13C-correlation techniques, as well as chemical transformations. Six diterpenes were tested against Mycobacterium tuberculosis and M. avium, but showed no significant activities with minimum inhibitory concentrations of > 100 μg ml−1
| Item Type: | Article |
|---|---|
| Additional Information: | Financial support from NIAID, National Institute of Health, under contract No. Y02-AI-30123 is gratefully acknowledged. |
| Uncontrolled Keywords: | Solidago rugosa; Asteraceae; Astereae; diterpenes; clerodanes; labdanes; kauranes; ent-abietanes |
| Author Affiliation: | Department of Chemistry College of Basic Sciences, Louisiana State University, Baton Rouge, Louisiana 70803, U.S.A. |
| Subjects: | Plant Physiology and Biochemistry > Plant Physiology Plant Physiology and Biochemistry > Biochemistry |
| Divisions: | General |
| Depositing User: | Mr Siva Shankar |
| Date Deposited: | 12 Aug 2013 10:37 |
| Last Modified: | 12 Aug 2013 10:37 |
| Official URL: | http://dx.doi.org/10.1016/0031-9422(94)00625-4 |
| URI: | http://eprints.icrisat.ac.in/id/eprint/11429 |
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